Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 20/20 | 0.82 |
| ▸ | F2 | P00734 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583992 | 0.86 | F2R (0.67) | F2RF2 | |
| SCHEMBL22022656 | 0.86 | F2R (0.86) | F2RF2 | |
| SCHEMBL14090294 | 0.83 | F2R (0.68) | F2RF2 | |
| SCHEMBL4263176 | 0.82 | F2R (0.85) | F2RF2 | |
| SCHEMBL13945253 | 0.80 | F2R (0.74) | F2RF2 | |
| SCHEMBL14583978 | 0.78 | F2R (0.77) | F2RF2 | |
| SCHEMBL14090286 | 0.78 | F2R (0.68) | F2RF2 | |
| SCHEMBL14583985 | 0.76 | F2R (0.52) | F2RF2 | |
| SCHEMBL12340155 | 0.75 | F2R (0.67) | F2RF2 | |
| SCHEMBL14090284 | 0.75 | F2R (0.76) | F2RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |