⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608862 | 0.79 | EHMT2 (0.40) | — | |
| SCHEMBL20038137 | 0.75 | PRMT3 (0.37) | — | |
| SCHEMBL20038235 | 0.74 | GRM4 (0.30) | — | |
| SCHEMBL9473737 | 0.71 | TDP1 (0.41) | — | |
| SCHEMBL20037911 | 0.71 | — | — | |
| SCHEMBL1412540 | 0.70 | — | — | |
| SCHEMBL9453859 | 0.69 | — | — | |
| SCHEMBL1848524 | 0.69 | — | — | |
| SCHEMBL2376776 | 0.69 | — | — | |
| SCHEMBL612658 | 0.69 | EHMT2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4655970-A | ONE STEP | CIBA-GEIGY AG (CH) | 1987-04-07 | — | — | US | claimed |
| US-4393007-A | ONE STEP PRODUCTION OF ANTHRAQUINONE DYES FROM 1-NITRO-ANTHRAQUINONE | CIBA-GEIGY AG (CH) | 1983-07-12 | — | — | US | claimed |
| US-12559592-B2 | Branched amorphous polyamide (co)polymers and methods of making and using same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-02-24 | — | — | US | disclosed |
| US-20230167243-A1 | BRANCHED AMORPHOUS POLYAMIDE (CO)POLYMERS AND METHODS OF MAKING AND USING SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2023-06-01 | — | — | US | disclosed |
| EP-4136185-A1 | BRANCHED AMORPHOUS POLYAMIDE (CO)POLYMERS AND METHODS OF MAKING AND USING SAME | 3M Innovative Properties Company (US) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021209895-A1 | BRANCHED AMORPHOUS POLYAMIDE (CO)POLYMERS AND METHODS OF MAKING AND USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-10-21 | — | — | WO | disclosed |
| US-7977342-B2 | HCV inhibiting bi-cyclic pyrimidines | TIBOTEC-VIRCO VIROLOGY BVBA (BE) | 2011-07-12 | — | — | US | disclosed |
| EP-1608631-A4 | BI-CYCLIC PYRIMIDINE INHIBITORS OF TGF BETA | SCIOS INC (US) | 2008-08-20 | — | — | EP | disclosed |
| US-20070155716-A1 | HCV INHIBITING BI-CYCLIC PYRIMIDINES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2007-07-05 | — | — | US | disclosed |
| US-7223766-B2 | Bi-cyclic pyrimidine inhibitors of TGFβ | SCIOS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| EP-1608631-A2 | BI-CYCLIC PYRIMIDINE INHIBITORS OF TGF BETA | SCIOS INC. (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2005077906-A1 | NOVEL GUANIDINYL-SUBSTITUTED HYDROXY-6-PHENYLPHENENTHRIDINES AS EFFECTIVE PHOSPHODIESTERASE (PDE) 4 INHIBITORS | ALTANA PHARMA AG (DE) | 2005-08-25 | — | — | WO | disclosed |
| US-20050004143-A1 | Bi-cyclic pyrimidine inhibitors of TGFbeta | SCIOS, INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2004087056-A2 | BI-CYCLIC PYRIMIDINE INHIBITORS OF TGFβ | SCIOS INC. (US) | 2004-10-14 | — | — | WO | disclosed |
| EP-0836613-A1 | WATER-SOLUBLE ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1996040707-A1 | WATER-SOLUBLE ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4655970-A | ONE STEP | CIBA-GEIGY AG (CH) | 1987-04-07 | — | — | US | disclosed |
| EP-0103381-A1 | Substituted anthra(1,9-cd)pyrazol-6(2H)-ones | WARNER-LAMBERT COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4393007-A | ONE STEP PRODUCTION OF ANTHRAQUINONE DYES FROM 1-NITRO-ANTHRAQUINONE | CIBA-GEIGY AG (CH) | 1983-07-12 | — | — | US | disclosed |