Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | TSPO | P30536 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15785992 | 0.99 | L3MBTL1 (0.42) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL15785994 | 0.98 | KDM4E (0.41) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL19626194 | 0.97 | PIM3 (0.37) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL18505404 | 0.97 | PIM3 (0.37) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL19626192 | 0.97 | PIM3 (0.37) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL24257888 | 0.97 | KDM4E (0.42) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL22257957 | 0.96 | L3MBTL1 (0.44) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL15786080 | 0.95 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL22257955 | 0.95 | L3MBTL1 (0.43) | KDM4EATML3MBTL1PTGER4PIM3 | |
| SCHEMBL12093280 | 0.95 | KDM4E (0.43) | KDM4EATML3MBTL1PTGER4PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200168810-A1 | COMPOSITION FOR ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |