Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL539245 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL5492149 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL28994812 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL10800799 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL28881559 | 0.86 | NFKB1 (0.40) | — | |
| Ethylenediamine SCHEMBL11318466 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL9357349 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL6810759 | 0.86 | NFKB1 (0.40) | — | |
| Ethylenediamine SCHEMBL10537063 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL1532494 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8617437-B2 | Flame retardant and flame retardant composition using same, molded article thereof, and electric wire with coating | SUN ALLOMER LTD. (JP) | 2013-12-31 | — | — | US | disclosed |
| US-8304609-B2 | Root-knot nematode-resistance gene and application thereof | UNIVERSITY OF TSUKUBA (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8088723-B2 | Polyaluminum compositions | THE CLOROX COMPANY (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110162102-A1 | Novel root-knot-nematode-resistance gene and application thereof | UNIVERSITY OF TSUKUBA, (JP) | 2011-06-30 | — | — | US | disclosed |
| US-20100212930-A1 | FLAME RETARDANT AND FLAME RETARDANT COMPOSITION USING SAME, MOLDED ARTICLE THEREOF, AND ELECTRIC WIRE WITH COATING | SUN ALLOMER LTD (JP) | 2010-08-26 | — | — | US | disclosed |
| US-20100113320-A1 | Polyaluminum Compostions | THE CLOROX COMPANY (US) | 2010-05-06 | — | — | US | disclosed |