SCHEMBL220281

SCHEMBL220281

CC(C)(C)OC(=O)NCCCCCN

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.71
MAOA P21397 1/20 0.66
MAOB P27338 1/20 0.66
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
GAA P10253 1/20 0.57
CA1 P00915 8/20 0.56
CA2 P00918 8/20 0.56
CA12 O43570 6/20 0.56
CA9 Q16790 6/20 0.56
PAOX Q6QHF9 2/20 0.55
EPHX1 P07099 2/20 0.44
CYP3A4 P08684 1/20 0.44
LMNA P02545 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL989107 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL964035 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL1309451 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL1206249 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL146037 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL5866373 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL1286925 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL368074 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
Hydrochloric Acid SCHEMBL2417149 0.98 TDP1 (0.69) TDP1MAOAMAOBMEN1KMT2A
Hydrochloric Acid SCHEMBL3231613 0.98 TDP1 (0.69) TDP1MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1045 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396190-B Preparation method of halogenated amide group hydrogel monomer 郑州玛特瑞斯生物科技有限公司 2024-11-15 CN claimed
CN-118831053-A Nanometer delivery system of nucleotide drug and preparation method and application thereof 中国科学院苏州纳米技术与纳米仿生研究所 2024-10-25 CN claimed
CN-118005556-A COX-2 targeted inhibition photosensitizer capable of activating tumor cell apoptosis and preparation method and application thereof 大连理工大学 2024-05-10 CN claimed
CN-114736264-B Tau protein visual PROTAC degradation compound and preparation method and application thereof 华东师范大学 2024-04-02 CN claimed
CN-116574081-B Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-09-05 CN claimed
CN-116574081-A Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-08-11 CN claimed
CN-116396190-A Preparation method of halogenated amide group hydrogel monomer 郑州玛特瑞斯生物科技有限公司 2023-07-07 CN claimed
CN-116354901-A Thiazolidinedione compound and preparation method and application thereof 郑州大学 2023-06-30 CN claimed
CN-115873058-A Novel FXR fluorescent probe compound and preparation method and application thereof 广州国家实验室 2023-03-31 CN claimed
CN-112898193-B Indole aryl sulfone derivative and preparation method and application thereof 山东大学 2022-08-05 CN claimed
WO-2004098589-A1 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES ELAN PHARMACEUTICALS, INC. (US) 2004-11-18 WO claimed
US-20040157217-A1 Nucleic acid-binding polymers VERIDIAN SYSTEMS DIVISION 2004-08-12 US claimed
EP-1140895-B1 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO (JP) 2004-03-24 EP claimed
US-6590061-B1 Synthetic polypeptide or peptides having narrow molecular weight distribution used as telechelic polymers for synthesis of block or graft copolymers INSTITUTE OF MACROMOLECULAR CHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 2003-07-08 US claimed
EP-1088020-B1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2002-12-18 EP claimed
CN-1343206-A Cyclocompound FUJISAWA PHARMACEUTICAL CO (JP) 2002-04-03 CN claimed
EP-1140895-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-10-10 EP claimed
EP-1088020-A1 FUNCTIONALISED POLYMERS OF ALPHA-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2001-04-04 EP claimed
WO-2000040576-A2 THIOPYRAN COMPOUNDS AS INHIBITORS OF MMP FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-07-13 WO claimed
WO-1999064495-A1 FUNCTIONALISED POLYMERS OF α-AMINO ACIDS AND THE METHOD OF PREPARATION THEREOF ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO claimed