Sugi Predict

Sugi Predict / Compounds / SCHEMBL989107

SCHEMBL989107

SCHEMBL989107

CC(C)(C)OC(=O)NCCCCCCCCCCCCN

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.71
▸ MAOA P21397 1/20 0.66
▸ MAOB P27338 1/20 0.66
▸ MEN1 O00255 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ GAA P10253 1/20 0.57
▸ CA1 P00915 8/20 0.56
▸ CA2 P00918 8/20 0.56
▸ CA12 O43570 6/20 0.56
▸ CA9 Q16790 6/20 0.56
▸ PAOX Q6QHF9 2/20 0.55
▸ EPHX1 P07099 2/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ LMNA P02545 1/20 0.43
▸ TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL964035 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL1309451 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL1206249 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL146037 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL5866373 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL220281 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL1286925 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
SCHEMBL368074 1.00 TDP1 (0.71) TDP1MAOAMAOBMEN1KMT2A
Hydrochloric Acid SCHEMBL2417149 0.98 TDP1 (0.69) TDP1MAOAMAOBMEN1KMT2A
Hydrochloric Acid SCHEMBL3231613 0.98 TDP1 (0.69) TDP1MAOAMAOBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116574081-B Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-09-05 — — CN claimed
CN-116574081-A Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-08-11 — — CN claimed
US-20250367166-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE SCRIPPS RESEARCH INST (US) 2025-12-04 — — US disclosed
US-20250114461-A1 CDK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-04-10 — — US disclosed
CN-118994300-A Protein degradation targeting chimeric and application thereof 沈阳药科大学 2024-11-22 — — CN disclosed
US-12097261-B2 CDK2 degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-09-24 — — US disclosed
CN-117715904-A CDK2 degrading agents and uses thereof 凯麦拉医疗公司 2024-03-15 — — CN disclosed
EP-4334307-A1 CDK2 DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2024-03-13 — — EP disclosed
CN-116574081-B Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-09-05 — — CN disclosed
CN-116574081-A Chlorogenic acid-Huang Qinsu conjugate and preparation method and application thereof 江西省科学院应用化学研究所 2023-08-11 — — CN disclosed
US-20230110180-A1 CDK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-04-13 — — US disclosed
WO-2009140467-A1 OXOBENZINDOLIZINOQUINOLINES AND USES THEREOF PURDUE RESEARCH FOUNDATION (US) 2009-11-19 — — WO disclosed
EP-2065406-A1 POLYMER HAVING VISIBILITY IN MAGNETIC RESONANCE IMAGE AND SURFACE LUBRICITY AND MEDICAL DEVICE Terumo Kabushiki Kaisha (JP) 2009-06-03 — — EP disclosed
US-20080318995-A1 N-Substituted Indenoisoquinolines and Syntheses Thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-12-25 — — US disclosed
EP-1960366-A2 N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF Purdue Research Foundation (US) 2008-08-27 — — EP disclosed
EP-1513538-A4 NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS MIRUS BIO CORP (US) 2007-08-22 — — EP disclosed
WO-2007059008-A2 N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF PURDUE RESEARCH FOUNDATION (US) 2007-05-24 — — WO disclosed
EP-1513538-A2 NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS Mirus Corporation (US) 2005-03-16 — — EP disclosed
US-20030235916-A1 Novel methods for the delivery of polynucleotides to cells ROCHE MADISON INC. 2003-12-25 — — US disclosed
WO-2003106636-A2 NOVEL METHODS FOR THE DELIVERY OF POLYNUCLEOTIDES TO CELLS MIRUS CORPORATION (US) 2003-12-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080318995-A1 N-Substituted Indenoisoquinolines and Syntheses Thereof GNAQ, NRAS, NPM1 TDP1 1868/4885MAOA 1700/4885MAOB 937/4885
US-12097261-B2 CDK2 degraders and uses thereof CDK2, CDK20, CDK1 TDP1 443/4885MAOA 2622/4885MAOB 2338/4885
US-20250114461-A1 CDK2 DEGRADERS AND USES THEREOF CDK2, CDK20, CDK1 TDP1 443/4885MAOA 2622/4885MAOB 2338/4885
US-20250367166-A1 NEXT GENERATION DIPROVOCIMS THAT ACTIVATE THE INNATE AND ADAPTIVE IMMUNE RESPONSE TLR1, TLR4, TLR3 TDP1 2212/4885MAOA 4248/4885MAOB 4102/4885
US-20230110180-A1 CDK2 DEGRADERS AND USES THEREOF CDK2, CDK20, CDK1 TDP1 443/4885MAOA 2622/4885MAOB 2338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.