Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811273 | 0.82 | TET2 (0.36) | — | |
| SCHEMBL2139826 | 0.80 | GRM2 (0.39) | TP53TSHRTDP1ALDH1A1CYP2D6 | |
| SCHEMBL4580237 | 0.76 | TSHR (0.46) | TP53TSHRTDP1ALDH1A1ACACB | |
| SCHEMBL8998339 | 0.74 | CYP1A2 (0.40) | TP53ALDH1A1HIF1ACYP2D6GRM2 | |
| SCHEMBL22028550 | 0.74 | ACACB (0.38) | TP53TSHRTDP1ALDH1A1ACACB | |
| SCHEMBL5704287 | 0.74 | TET2 (0.46) | TP53TSHRALDH1A1ACACBACACA | |
| SCHEMBL1172737 | 0.74 | MAPT (0.32) | TSHR | |
| SCHEMBL7382813 | 0.74 | GRM2 (0.40) | TP53ALDH1A1HIF1ACYP2D6GRM2 | |
| SCHEMBL22028548 | 0.72 | ACACB (0.41) | TP53ALDH1A1ACACBACACACYP1A2 | |
| SCHEMBL5172333 | 0.72 | TSHR (0.33) | TP53TSHRALDH1A1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3491044-B1 | METHOD OF REGIOSELECTIVE SYNTHESIS OF POLYESTERS FROM ASYMMETRIC DIOLS | VERSALIS SPA (IT) | 2020-08-26 | — | — | EP | disclosed |
| US-20200181319-A1 | METHOD OF REGIOSELECTIVE SYNTHESIS OF POLYESTERS FROM ASYMMETRIC DIOLS | VERSALIS S.P.A. (IT) | 2020-06-11 | — | — | US | disclosed |