Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 16/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.52 |
| ▸ | GNRHR | P30968 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22071232 | 0.88 | CLPP (0.66) | CLPPCYP3A4GNRHR | |
| SCHEMBL22028745 | 0.88 | CLPP (0.64) | CLPPCYP3A4GNRHR | |
| SCHEMBL22071230 | 0.88 | CLPP (0.55) | CLPPGNRHR | |
| SCHEMBL22028758 | 0.87 | CLPP (0.65) | CLPPCYP3A4GNRHR | |
| SCHEMBL22028764 | 0.83 | CLPP (0.58) | CLPP | |
| SCHEMBL24914476 | 0.82 | CLPP (0.72) | CLPPCYP3A4GNRHR | |
| SCHEMBL26705470 | 0.80 | CLPP (0.56) | CLPPCYP3A4P2RX3GNRHR | |
| SCHEMBL31315767 | 0.80 | CLPP (0.56) | CLPPCYP3A4 | |
| SCHEMBL24914731 | 0.80 | CLPP (0.68) | CLPPCYP3A4GNRHR | |
| SCHEMBL24914446 | 0.80 | CLPP (1.00) | CLPPCYP3A4GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715162-B | Protein kinase modulators | 南京盖特医药技术有限公司 | 2025-03-21 | — | — | CN | disclosed |
| US-11091477-B2 | Protein kinase regulators | Madera Therapeutics, LLC (US) | 2021-08-17 | — | — | US | disclosed |
| US-11091477-B2 | Protein kinase regulators | Madera Therapeutics, LLC (US) | 2021-08-17 | — | — | US | disclosed |
| US-20200181139-A1 | Protein Kinase Regulators | Madera Therapeutics, LLC | 2020-06-11 | — | — | US | disclosed |
| US-20200181139-A1 | Protein Kinase Regulators | Madera Therapeutics, LLC | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091477-B2 | Protein kinase regulators | MAP3K1, MAP3K6, MAP3K20 | CLPP 1459/4885CYP3A4 4298/4885P2RX3 2685/4885 |
| US-20200181139-A1 | Protein Kinase Regulators | MAP3K1, MAP3K6, MAP3K20 | CLPP 1459/4885CYP3A4 4298/4885P2RX3 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.