Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202910 | 1.00 | DDB1 (0.44) | DDB1CRBNNPC1RAB9AHTR2C | |
| SCHEMBL25176242 | 0.82 | DDB1 (0.48) | DDB1CRBNNPC1RAB9AHTR2C | |
| SCHEMBL31229229 | 0.80 | DDB1 (0.49) | DDB1CRBNNPC1RAB9AHTR2C | |
| SCHEMBL11285680 | 0.80 | HTR2C (0.45) | DDB1CRBNNPC1RAB9AHTR2C | |
| SCHEMBL483149 | 0.75 | DDB1 (0.33) | DDB1CRBNSMN1; SMN2 | |
| SCHEMBL1914273 | 0.75 | DDB1 (0.33) | DDB1CRBNSMN1; SMN2 | |
| SCHEMBL29202479 | 0.74 | STS (0.39) | — | |
| SCHEMBL1399082 | 0.73 | CTRB1 (0.43) | DDB1CRBNNPC1RAB9AHTR2C | |
| SCHEMBL17024449 | 0.72 | SMN1; SMN2 (0.43) | NPC1RAB9AHTR2CSMN1; SMN2 | |
| SCHEMBL4522759 | 0.72 | NPC1 (0.56) | NPC1RAB9AHTR2CL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977343-B2 | Adenine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-12 | — | — | US | disclosed |