Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2202927 | 1.00 | MCHR1 (0.47) | MCHR1KMT2ACCR2ELANEMEN1 | |
| SCHEMBL2203098 | 0.89 | KMT2A (0.45) | MCHR1KMT2ANPSR1 | |
| SCHEMBL2203102 | 0.89 | KMT2A (0.45) | MCHR1KMT2ANPSR1 | |
| SCHEMBL13973770 | 0.89 | KMT2A (0.42) | MCHR1KMT2ATSHRHTT | |
| SCHEMBL2200093 | 0.85 | KMT2A (0.48) | KMT2AELANEMEN1LMNATSHR | |
| SCHEMBL2201573 | 0.84 | KMT2A (0.43) | KMT2AELANEMEN1LMNATSHR | |
| SCHEMBL2204251 | 0.82 | ELANE (0.48) | KMT2AELANEMEN1LMNATSHR | |
| SCHEMBL2201732 | 0.82 | MALT1 (0.40) | MCHR1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL2200676 | 0.82 | MALT1 (0.40) | MCHR1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL2200679 | 0.82 | MALT1 (0.40) | MCHR1KMT2AMEN1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977358-B2 | Pyrazol derivatives | HOFFMANN-LA ROCHE INC. (US) | 2011-07-12 | — | — | US | disclosed |