SCHEMBL22029358

SCHEMBL22029358

CC(C)(C)OC(=O)CCCCCCCCCCCC#Cc1ccc(S(N)(=O)=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 1/20 0.49
ITGA4 P13612 1/20 0.49
CA2 P00918 15/20 0.46
CA1 P00915 14/20 0.46
CA9 Q16790 11/20 0.46
CA12 O43570 9/20 0.46
CA14 Q9ULX7 1/20 0.43
CA7 P43166 2/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
CA4 P22748 1/20 0.40
MMP2 P08253 3/20 0.39
MMP12 P39900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31682090 1.00 ITGB1 (0.49) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682046 1.00 ITGB1 (0.49) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682059 0.94 CA1 (0.47) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682056 0.94 CA1 (0.47) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682092 0.91 ITGB1 (0.47) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682116 0.91 ITGB1 (0.47) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682079 0.91 ITGB1 (0.47) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682083 0.89 CA1 (0.49) ITGB1ITGA4CA2CA1CA9
SCHEMBL31682108 0.89 CA1 (0.49) ITGB1ITGA4CA2CA1CA9
SCHEMBL31681999 0.86 CA1 (0.44) ITGB1ITGA4CA2CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893934-B1 INSULIN CONJUGATES SANOFI SA (FR) 2025-09-10 EP disclosed
US-20250206798-A1 INSULIN CONJUGATES SANOFI SA (FR) 2025-06-26 US disclosed
US-12195510-B2 Insulin conjugates SANOFI (FR) 2025-01-14 US disclosed
US-20220048968-A1 INSULIN CONJUGATES SANOFI (FR) 2022-02-17 US disclosed
US-20220048968-A1 INSULIN CONJUGATES SANOFI (FR) 2022-02-17 US disclosed
EP-3893934-A1 INSULIN CONJUGATES SANOFI (FR) 2021-10-20 EP disclosed
EP-3894391-A1 PEPTIDE BINDER SANOFI (FR) 2021-10-20 EP disclosed
CN-113423691-A Peptide binding agents 赛诺菲 2021-09-21 CN disclosed
CN-113395982-A Insulin conjugates 赛诺菲 2021-09-14 CN disclosed
WO-2020120463-A1 INSULIN CONJUGATES SANOFI (FR) 2020-06-18 WO disclosed
WO-2020120479-A1 PEPTIDE BINDER SANOFI (FR) 2020-06-18 WO disclosed
WO-2020120463-A1 INSULIN CONJUGATES SANOFI (FR) 2020-06-18 WO disclosed
WO-2020120479-A1 PEPTIDE BINDER SANOFI (FR) 2020-06-18 WO disclosed
US-20200181223-A1 INSULIN CONJUGATES SANOFI (FR) 2020-06-11 US disclosed
US-20200181223-A1 INSULIN CONJUGATES SANOFI (FR) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200181223-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R ITGB1 2907/4885ITGA4 3171/4885CA2 1521/4885
US-20220048968-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R ITGB1 2907/4885ITGA4 3171/4885CA2 1521/4885
US-12195510-B2 Insulin conjugates IAPP, INSR, IGF1R ITGB1 2907/4885ITGA4 3171/4885CA2 1521/4885
US-20250206798-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R ITGB1 2907/4885ITGA4 3171/4885CA2 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.