Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 12/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3747991 | 0.85 | NSD2 (0.44) | MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5682164 | 0.83 | CYP11B1 (0.43) | KMT2ACYP1A2 | |
| SCHEMBL3780260 | 0.82 | NR2E1 (0.38) | CYP1A2 | |
| SCHEMBL12510626 | 0.81 | SIRT2 (0.36) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL28146943 | 0.80 | SIRT2 (0.36) | MEN1KMT2AHTTTDP1CYP1A2 | |
| SCHEMBL1479176 | 0.79 | NAPRT (0.47) | MEN1KMT2ATDP1ALDH1A1CYP1A2 | |
| SCHEMBL7641514 | 0.79 | P2RX7 (0.40) | KMT2A | |
| SCHEMBL670904 | 0.77 | CYP11B1 (0.43) | TDP1L3MBTL1ALDH1A1HPGDTSHR | |
| SCHEMBL3751804 | 0.77 | KDM4E (0.38) | MEN1MAPTKMT2AHTTNPSR1 | |
| SCHEMBL4824432 | 0.77 | KDM4E (0.44) | MEN1MAPTKMT2AHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079706-B1 | METHOD FOR PREPARING MEDETOMIDINE AND ITS SALTS | GRINDEKS JSC (LV) | 2011-07-20 | — | — | EP | disclosed |