Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 4/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL13386757 | 0.76 | IDO1 (0.51) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL21540839 | 0.75 | IDO1 (0.54) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL24368019 | 0.75 | IDO1 (0.54) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL21216406 | 0.73 | IDO1 (0.51) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL22079091 | 0.72 | IDO1 (0.53) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL28592498 | 0.72 | IDO1 (0.53) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL2611042 | 0.71 | IDO1 (0.55) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL20353958 | 0.69 | IDO1 (0.53) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL23021781 | 0.69 | IDO1 (0.60) | IDO1METNOS1AXLTRPV1 | |
| SCHEMBL22079063 | 0.67 | TRPV1 (0.43) | IDO1NOS1AXLTRPV1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3891142-A1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2021-10-13 | — | — | EP | disclosed |
| WO-2020114949-A1 | HETEROAROMATIC COMPOUNDS AS VANIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-11 | — | — | WO | disclosed |