Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033014 | 0.91 | RXFP1 (0.49) | RXFP1P2RX1SLC2A1P2RX4P2RX7 | |
| SCHEMBL22032910 | 0.90 | P2RX1 (0.45) | TP53P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL22033381 | 0.89 | RXFP1 (0.52) | RXFP1TP53P2RX1SLC2A1P2RX4 | |
| SCHEMBL22033146 | 0.87 | TMPRSS4 (0.41) | TP53P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL22032960 | 0.87 | TP53 (0.52) | TP53P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL22082883 | 0.83 | TP53 (0.48) | TP53P2RX1MEN1KMT2A | |
| SCHEMBL22082834 | 0.82 | BACE1 (0.42) | TP53P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL22032909 | 0.81 | P2RX1 (0.46) | P2RX1P2RX4P2RX7TMPRSS4MEN1 | |
| SCHEMBL22033345 | 0.81 | TP53 (0.49) | TP53P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL22033920 | 0.80 | TP53 (0.44) | TP53P2RX1P2RX4P2RX7TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |