Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033379 | 0.91 | RXFP1 (0.53) | RXFP1P2RX1SLC2A1P2RX4P2RX7 | |
| SCHEMBL22033341 | 0.91 | P2RX1 (0.47) | TP53P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL22033016 | 0.89 | RXFP1 (0.48) | RXFP1TP53P2RX1SLC2A1P2RX4 | |
| SCHEMBL22033574 | 0.88 | TP53 (0.45) | TP53P2RX1P2RX4P2RX7TMPRSS4 | |
| SCHEMBL22033050 | 0.87 | TP53 (0.55) | TP53P2RX1P2RX4P2RX7MEN1 | |
| SCHEMBL22033674 | 0.85 | TP53 (0.53) | TP53MEN1KMT2AKIF18A | |
| SCHEMBL22081964 | 0.85 | TP53 (0.53) | TP53CSF1RMEN1KMT2AKIF18A | |
| SCHEMBL22032869 | 0.84 | MEN1 (0.53) | TP53MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22032948 | 0.83 | TP53 (0.54) | TP53MEN1KMT2APTGS1 | |
| SCHEMBL22033064 | 0.81 | TP53 (0.54) | TP53P2RX1P2RX4P2RX7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |