Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033214 | 0.95 | TP53 (0.38) | MAPTL3MBTL1KDM4EHPGDP2RX1 | |
| SCHEMBL22033217 | 0.93 | TP53 (0.39) | MAPTL3MBTL1KDM4EHPGDP2RX1 | |
| SCHEMBL22033322 | 0.90 | L3MBTL1 (0.36) | MAPTL3MBTL1KDM4EHPGDP2RX1 | |
| SCHEMBL22033248 | 0.89 | TP53 (0.51) | MAPTL3MBTL1KDM4EHPGDP2RX1 | |
| SCHEMBL22033918 | 0.89 | MAPT (0.40) | MAPTP2RX1TMPRSS4TP53RAB9A | |
| SCHEMBL22032864 | 0.87 | KMT2A (0.46) | MAPTL3MBTL1KDM4EHPGDP2RX1 | |
| SCHEMBL22033344 | 0.87 | P2RX1 (0.40) | MAPTP2RX1TP53RAB9ANPC1 | |
| SCHEMBL22032909 | 0.85 | P2RX1 (0.46) | MAPTP2RX1TMPRSS4KMT2AMEN1 | |
| SCHEMBL22033040 | 0.84 | TP53 (0.41) | MAPTL3MBTL1KDM4EHPGDP2RX1 | |
| SCHEMBL22033215 | 0.84 | TP53 (0.48) | MAPTL3MBTL1KDM4EHPGDP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |