Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033250 | 0.90 | TP53 (0.53) | FADS1RXFP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL22033048 | 0.87 | MEN1 (0.51) | FADS1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL22033380 | 0.86 | ACKR3 (0.41) | SMN1; SMN2KMT2AMEN1HTTCYP1A2 | |
| SCHEMBL22032946 | 0.85 | KMT2A (0.51) | SMN1; SMN2KMT2AMEN1HTTCYP1A2 | |
| SCHEMBL22033357 | 0.84 | TP53 (0.47) | RXFP1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL22033673 | 0.84 | MEN1 (0.48) | SMN1; SMN2KMT2AMEN1HTTCYP1A2 | |
| SCHEMBL22032868 | 0.84 | MEN1 (0.53) | FADS1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL22033379 | 0.83 | RXFP1 (0.53) | RXFP1SMN1; SMN2KMT2AMEN1HTT | |
| SCHEMBL22033502 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1HTTCYP1A2 | |
| SCHEMBL22032864 | 0.81 | KMT2A (0.46) | SMN1; SMN2KMT2AMEN1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |