Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033249 | 0.90 | FADS1 (0.46) | TP53FADS1KIF18ARXFP1MAPT | |
| SCHEMBL22033050 | 0.87 | TP53 (0.55) | TP53FADS1KIF18AMAPTSMN1; SMN2 | |
| SCHEMBL22033383 | 0.86 | TP53 (0.51) | TP53KIF18AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL22032948 | 0.85 | TP53 (0.54) | TP53MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22081964 | 0.85 | TP53 (0.53) | TP53KIF18AMAPTMEN1KMT2A | |
| SCHEMBL22033674 | 0.85 | TP53 (0.53) | TP53KIF18AMAPTMEN1KMT2A | |
| SCHEMBL22033354 | 0.84 | TP53 (0.59) | TP53KIF18ARXFP1MAPTSMN1; SMN2 | |
| SCHEMBL22032869 | 0.84 | MEN1 (0.53) | TP53SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL22081951 | 0.83 | TP53 (0.53) | TP53MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22032916 | 0.83 | TP53 (0.52) | TP53KIF18ARXFP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |