Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033062 | 0.95 | KMT2A (0.46) | KMT2AMEN1P2RX1P2RX4P2RX7 | |
| SCHEMBL22032964 | 0.92 | KMT2A (0.51) | KMT2AMEN1P2RX1P2RX4P2RX7 | |
| SCHEMBL22033012 | 0.90 | KMT2A (0.43) | KMT2AMEN1P2RX1TP53CSF1R | |
| SCHEMBL22033280 | 0.90 | TP53 (0.52) | KMT2AMEN1P2RX1P2RX4P2RX7 | |
| SCHEMBL22033572 | 0.88 | MEN1 (0.45) | KMT2AMEN1P2RX1P2RX4P2RX7 | |
| SCHEMBL22033337 | 0.88 | KMT2A (0.47) | KMT2AMEN1P2RX1TP53CSF1R | |
| SCHEMBL22032991 | 0.88 | P2RX1 (0.38) | KMT2AMEN1P2RX1P2RX4P2RX7 | |
| SCHEMBL22033048 | 0.85 | MEN1 (0.51) | KMT2AMEN1P2RX1P2RX4P2RX7 | |
| SCHEMBL22032874 | 0.85 | KMT2A (0.44) | KMT2AMEN1P2RX1CYP1A2CYP2C9 | |
| SCHEMBL22033338 | 0.84 | P2RX1 (0.48) | KMT2AMEN1P2RX1P2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |