Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 2/20 | 0.34 |
| ▸ | ATF1 | P18846 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22033344 | 0.95 | P2RX1 (0.40) | P2RX1P2RX4P2RX7TP53MAPT | |
| SCHEMBL22033918 | 0.92 | MAPT (0.40) | P2RX1P2RX4P2RX7TP53MAPT | |
| SCHEMBL22033217 | 0.90 | TP53 (0.39) | P2RX1P2RX4P2RX7TP53MAPT | |
| SCHEMBL22032992 | 0.90 | TP53 (0.47) | P2RX1P2RX4P2RX7GRM4TP53 | |
| SCHEMBL22033143 | 0.88 | P2RX1 (0.42) | P2RX1P2RX4P2RX7MAPTMEN1 | |
| SCHEMBL22033279 | 0.88 | KMT2A (0.47) | P2RX1P2RX4P2RX7GRM4TP53 | |
| SCHEMBL22033253 | 0.88 | MEN1 (0.38) | P2RX1P2RX4P2RX7TP53MAPT | |
| SCHEMBL22033214 | 0.88 | TP53 (0.38) | P2RX1TP53MAPTMEN1KMT2A | |
| SCHEMBL22033587 | 0.86 | RAB9A (0.34) | P2RX1P2RX4P2RX7TP53MAPT | |
| SCHEMBL22033247 | 0.84 | MAPT (0.41) | P2RX1TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020117877-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2020-06-11 | — | — | WO | disclosed |