Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584659 | 0.79 | CYP2A6 (0.41) | NPC1SMN1; SMN2MAPTRAB9ACYP2A6 | |
| SCHEMBL10904256 | 0.78 | PTPN22 (0.48) | MAPTTDP1SIGMAR1KDM4E | |
| SCHEMBL29657743 | 0.76 | SIGMAR1 (0.54) | NPC1MAPTCYP2A6ALDH1A1ELANE | |
| SCHEMBL517207 | 0.76 | SIGMAR1 (0.54) | NPC1MAPTCYP2A6ALDH1A1ELANE | |
| SCHEMBL23560405 | 0.76 | POLB (0.47) | NPC1SMN1; SMN2MAPTRAB9APOLB | |
| Hydrochloric Acid SCHEMBL4747710 | 0.75 | SIGMAR1 (0.53) | NPC1MAPTCYP2A6ALDH1A1ELANE | |
| Bromide SCHEMBL7412701 | 0.75 | SIGMAR1 (0.53) | NPC1MAPTCYP2A6ALDH1A1ELANE | |
| SCHEMBL17065828 | 0.74 | MAPT (0.41) | NPC1SMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL2197815 | 0.74 | SIGMAR1 (0.36) | NPC1SMN1; SMN2MAPTRAB9ACYP2A6 | |
| SCHEMBL5535163 | 0.73 | PTPN1 (0.47) | NPC1SMN1; SMN2MAPTRAB9ANCEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964861-B1 | ACETYLENE-BASED POLYMER | NAT INST OF ADVANCED IND SCIEN (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-7977441-B2 | Acetylene-based polymer | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2011-07-12 | — | — | US | disclosed |
| US-20090253872-A1 | Acetylene-Based Polymer | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-1964861-A1 | ACETYLENE POLYMER | National Institute of Advanced Industrial Science and Technology (JP) | 2008-09-03 | — | — | EP | disclosed |