⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400038 | 0.89 | — | — | |
| SCHEMBL1579829 | 0.89 | — | — | |
| SCHEMBL168578 | 0.87 | — | — | |
| SCHEMBL553473 | 0.81 | — | — | |
| SCHEMBL10622609 | 0.79 | — | — | |
| SCHEMBL10622614 | 0.79 | — | — | |
| SCHEMBL8523616 | 0.75 | — | — | |
| SCHEMBL8920086 | 0.75 | — | — | |
| SCHEMBL432351 | 0.72 | — | — | |
| SCHEMBL815076 | 0.72 | NOS1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220373541-A1 | Tri-functional Crosslinking Reagents | ETH ZURICH (CH) | 2022-11-24 | — | — | US | disclosed |
| US-11385225-B2 | Tri-functional crosslinking reagents | ETH ZURICH (CH) | 2022-07-12 | — | — | US | disclosed |
| EP-3374348-B1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2021-11-24 | — | — | EP | disclosed |
| CN-108368051-B | Trifunctional crosslinking reagents | ETH苏黎世公司 | 2021-05-25 | — | — | CN | disclosed |
| US-10550093-B2 | Third generation taxoids and methods of using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180328922-A1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH ZURICH (CH) | 2018-11-15 | — | — | US | disclosed |
| EP-3374348-A1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH Zurich (CH) | 2018-09-19 | — | — | EP | disclosed |
| US-20180194744-A1 | Third Generation Taxoids and Methods of Using Same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-07-12 | — | — | US | disclosed |
| EP-3316880-A1 | THIRD GENERATION TAXOIDS AND METHODS OF USING SAME | The Research Foundation for The State University of New York (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9766235-B2 | Trifunctional crosslinking reagents | ETH ZURICH (CH) | 2017-09-19 | — | — | US | disclosed |
| WO-2017081069-A1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH ZURICH (CH) | 2017-05-18 | — | — | WO | disclosed |
| WO-2017004478-A1 | THIRD GENERATION TAXOIDS AND METHODS OF USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-01-05 | — | — | WO | disclosed |
| EP-2670755-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |
| EP-2942351-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |
| EP-2942351-A1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH Zurich (CH) | 2015-11-11 | — | — | EP | disclosed |
| US-20140011212-A1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZURICH (CH) | 2014-01-09 | — | — | US | disclosed |
| US-7981926-B2 | Fluorotaxoids | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-07-19 | — | — | US | disclosed |
| US-20090118355-A1 | Fluorotaxoids | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2009-05-07 | — | — | US | disclosed |
| WO-2008021242-A2 | FLUOROTAXOID-FATTY ACID CONJUGATES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007021957-A2 | FLUOROTAXOIDS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |