Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20988518 | 0.89 | ALOX5 (0.38) | ALOX5PIK3CDPIK3CBPRKDCPARP14 | |
| SCHEMBL24217972 | 0.88 | ALOX5 (0.38) | ALOX5PIK3CDPIK3CBPRKDCPARP14 | |
| SCHEMBL16452184 | 0.87 | ALOX5 (0.34) | ALOX5PIK3CDPIK3CBPRKDCPARP14 | |
| SCHEMBL16811135 | 0.86 | ALOX5 (0.41) | ALOX5PIK3CDPIK3CBPRKDCPARP14 | |
| SCHEMBL25660266 | 0.86 | ALOX5 (0.39) | ALOX5PIK3CDPIK3CBPRKDCPARP14 | |
| SCHEMBL22036113 | 0.85 | KDM4E (0.34) | — | |
| SCHEMBL23760200 | 0.85 | ALOX5 (0.32) | ALOX5PARP14 | |
| SCHEMBL24152246 | 0.85 | ALOX5 (0.36) | ALOX5PIK3CDPIK3CBPRKDCPARP14 | |
| SCHEMBL18593787 | 0.85 | ALOX5 (0.36) | ALOX5PIK3CDPIK3CBPRKDCPARP14 | |
| SCHEMBL19769880 | 0.85 | KDM4E (0.34) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2J2, CYP2D6 | ALOX5 1247/4885PIK3CD 1361/4885PIK3CB 1375/4885 |
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | ETV6, CYP2J2, CYP2D6 | ALOX5 1247/4885PIK3CD 1361/4885PIK3CB 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.