Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24797102 | 0.96 | KDM4E (0.35) | KDM4EATML3MBTL1PTGER4TSPO | |
| SCHEMBL22035874 | 0.91 | L3MBTL1 (0.39) | KDM4EATML3MBTL1PTGER4ABCG2 | |
| SCHEMBL15197839 | 0.88 | L3MBTL1 (0.41) | KDM4EATML3MBTL1PTGER4TSPO | |
| SCHEMBL23760161 | 0.88 | L3MBTL1 (0.47) | KDM4EATML3MBTL1PTGER4TSPO | |
| SCHEMBL23760169 | 0.88 | L3MBTL1 (0.47) | KDM4EATML3MBTL1PTGER4TSPO | |
| SCHEMBL24549724 | 0.87 | KDM4E (0.40) | KDM4EATML3MBTL1PTGER4TSPO | |
| SCHEMBL16675306 | 0.87 | L3MBTL1 (0.40) | KDM4EATML3MBTL1PTGER4TSPO | |
| SCHEMBL23119058 | 0.87 | L3MBTL1 (0.42) | KDM4EATML3MBTL1PTGER4TSPO | |
| SCHEMBL22035868 | 0.86 | KDM4E (0.34) | KDM4EATML3MBTL1KMT2A | |
| SCHEMBL25479819 | 0.86 | KDM4E (0.39) | KDM4EATML3MBTL1PTGER4TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630764-B1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR USE IN ELEKTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2J2, CYP2D6 | KDM4E 2237/4885ATM 4482/4885L3MBTL1 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.