Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036685 | 0.90 | MAPT (0.35) | MAPTL3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL22035868 | 0.87 | KDM4E (0.34) | MAPTL3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL23474714 | 0.86 | MAPT (0.34) | MAPTL3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL22036135 | 0.85 | MEN1 (0.38) | MAPTL3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL21449288 | 0.85 | MAPT (0.33) | MAPTL3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL19890653 | 0.85 | MAPT (0.33) | MAPTL3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL23487174 | 0.85 | MAPT (0.35) | MAPTL3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL22172035 | 0.84 | L3MBTL1 (0.32) | MAPTL3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL23474672 | 0.84 | MAPT (0.33) | MAPTL3MBTL1KDM4EMAPK1NPSR1 | |
| SCHEMBL23474657 | 0.84 | MAPT (0.33) | MAPTL3MBTL1KDM4EMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2J2, CYP2D6 | MAPT 2751/4885L3MBTL1 3859/4885KDM4E 2237/4885 |
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | ETV6, CYP2J2, CYP2D6 | MAPT 2751/4885L3MBTL1 3859/4885KDM4E 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.