Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22036066 | 0.91 | MAPT (0.42) | MAPTMAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL23474650 | 0.88 | MAPT (0.41) | MAPTMAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL26528760 | 0.85 | MAPT (0.40) | MAPTMAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL22036135 | 0.85 | MEN1 (0.38) | MAPTTSHRHSD17B10HPGDADORA2A | |
| SCHEMBL22036723 | 0.84 | MAPT (0.37) | MAPTMAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL19890595 | 0.84 | MAPT (0.41) | MAPTMAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL22035868 | 0.84 | KDM4E (0.34) | MAPTTSHRHSD17B10HPGDMEN1 | |
| SCHEMBL17265071 | 0.83 | MAPT (0.42) | MAPTMAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL17033559 | 0.83 | MAPT (0.40) | MAPTMAPK1NPSR1TSHRHSD17B10 | |
| SCHEMBL16067159 | 0.83 | MAPT (0.40) | MAPTMAPK1NPSR1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165252-A1 | HEXACYCLIC HETEROAROMATIC COMPOUNDS FOR ELECTRONIC DEVICES | ETV6, CYP2J2, CYP2D6 | MAPT 2751/4885MAPK1 3104/4885NPSR1 2731/4885 |
| US-11535619-B2 | Hexacyclic heteroaromatic compounds for electronic devices | ETV6, CYP2J2, CYP2D6 | MAPT 2751/4885MAPK1 3104/4885NPSR1 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.