SCHEMBL22037243

SCHEMBL22037243

Cc1cccc(N(N)C(=O)N(C)N)c1COc1ccc(F)c(-c2ccc(F)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.41
FFAR4 Q5NUL3 8/20 0.38
ANO1 Q5XXA6 2/20 0.36
F10 P00742 1/20 0.36
MCL1 Q07820 1/20 0.35
PPARD Q03181 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22038686 0.90 GYS1 (0.39) FFAR1FFAR4PPARD
SCHEMBL22038754 0.83 FFAR1 (0.41) FFAR1PPARD
SCHEMBL22038175 0.81 FFAR1 (0.40) FFAR1FFAR4ANO1PPARD
SCHEMBL22038711 0.80 FFAR1 (0.45) FFAR1FFAR4ANO1PPARD
SCHEMBL22038713 0.79 GYS1 (0.39) FFAR1PPARD
SCHEMBL22038166 0.79 CHRNA7 (0.36) MCL1PPARD
SCHEMBL22037228 0.77 PPARD (0.39) FFAR1PPARD
SCHEMBL21317993 0.77 PARP15 (0.41) FFAR1
SCHEMBL22037270 0.76 PTGER1 (0.43)
SCHEMBL20686712 0.76 MRGPRX4 (0.47) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2990404-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-05-27 EP disclosed