Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicyladehyde SCHEMBL7034198 | 0.72 | TRIM24 (0.62) | TRIM24TRIM33ERN1CA1CA2 | |
| Catechol SCHEMBL28758914 | 0.69 | TRIM24 (0.57) | TRIM24TRIM33ERN1MAPT | |
| SCHEMBL26083455 | 0.69 | ERN1 (0.62) | ERN1 | |
| Metacresol SCHEMBL4532236 | 0.69 | ACHE (0.59) | TRIM24TRIM33ERN1ALOX15ALDH1A1 | |
| Salicyladehyde SCHEMBL8647157 | 0.69 | TRIM24 (0.75) | TRIM24TRIM33ERN1ALOX12CA1 | |
| SCHEMBL38651955 | 0.68 | TRIM24 (0.50) | TRIM24TRIM33ERN1CA1CA2 | |
| Salicyladehyde SCHEMBL7090644 | 0.68 | TRIM24 (0.67) | TRIM24TRIM33ERN1CA1CA2 | |
| SCHEMBL172664 | 0.68 | ERN1 (0.58) | TRIM24TRIM33ERN1ALOX15ALDH1A1 | |
| SCHEMBL29951782 | 0.68 | ERN1 (0.58) | TRIM24TRIM33ERN1ALOX15ALDH1A1 | |
| Metacresol SCHEMBL28223396 | 0.68 | ACHE (0.57) | TRIM24TRIM33ERN1ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3656382-A1 | PERK AND IRE-1A INHIBITORS AGAINST NEURODEVELOPMENTAL DISORDERS | Université de Liège (BE) | 2020-05-27 | — | — | EP | disclosed |