Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22063762 | 0.97 | TSHR (0.41) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL20023215 | 0.96 | TSHR (0.47) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL16298992 | 0.96 | TSHR (0.47) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL21665520 | 0.93 | TSHR (0.44) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL21576977 | 0.93 | TSHR (0.44) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL18031017 | 0.92 | TSHR (0.44) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL23011621 | 0.90 | PTPN1 (0.43) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL14199417 | 0.90 | TSHR (0.47) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL17552001 | 0.89 | TSHR (0.48) | TSHRPAX8PRKCAAKT1PTK2 | |
| SCHEMBL18654280 | 0.88 | PTPN1 (0.52) | TSHRUSP2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200163987-A1 | METHODS AND COMPOSITIONS FOR TREATING A BLEEDING EVENT IN A SUBJECT HAVING HEMOPHILIA | BANK OF AMERICA, N.A. | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200163987-A1 | METHODS AND COMPOSITIONS FOR TREATING A BLEEDING EVENT IN A SUBJECT HAVING HEMOPHILIA | SERPINC1, SERPINE1, SERPINH1 | TSHR 4491/4885PAX8 2154/4885PRKCA 2865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.