Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 20/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 10/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22039416 | 0.79 | EP300 (0.62) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL31149079 | 0.79 | EP300 (0.62) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL17605189 | 0.79 | EP300 (0.62) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL17605191 | 0.79 | EP300 (0.62) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL21505423 | 0.77 | EP300 (0.70) | EP300CREBBP | |
| SCHEMBL23018063 | 0.74 | EP300 (0.73) | EP300CREBBP | |
| SCHEMBL23891532 | 0.74 | EP300 (0.42) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL23017945 | 0.73 | EP300 (0.73) | EP300CREBBP | |
| SCHEMBL24349905 | 0.72 | EP300 (0.35) | EP300CREBBPCYP3A4CYP2C8CYP2C9 | |
| SCHEMBL22040902 | 0.71 | HDAC6 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108500-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | 成都海创药业有限公司 | 2020-06-04 | — | — | WO | disclosed |