Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22039600 | 0.77 | EP300 (0.34) | — | |
| SCHEMBL22040124 | 0.71 | EP300 (0.43) | — | |
| SCHEMBL24350339 | 0.67 | EP300 (0.38) | — | |
| SCHEMBL22040804 | 0.67 | NR1H2 (0.34) | HDAC6 | |
| SCHEMBL23891784 | 0.67 | EP300 (0.35) | — | |
| SCHEMBL22039604 | 0.66 | EP300 (0.34) | — | |
| SCHEMBL17605990 | 0.64 | EP300 (0.42) | — | |
| SCHEMBL17605989 | 0.64 | EP300 (0.42) | — | |
| SCHEMBL22039701 | 0.64 | EP300 (0.42) | — | |
| SCHEMBL31149069 | 0.64 | EP300 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108500-A1 | HISTONE ACETYLASE P300 INHIBITOR AND USE THEREOF | 成都海创药业有限公司 | 2020-06-04 | — | — | WO | disclosed |