Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 17/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236088 | 0.89 | IDO1 (0.57) | IDO1GPR119HRH3 | |
| SCHEMBL12491393 | 0.89 | IDO1 (0.57) | IDO1GPR119HRH3 | |
| SCHEMBL22039280 | 0.89 | IDO1 (0.56) | IDO1 | |
| Hydrochloric Acid SCHEMBL21979354 | 0.88 | IDO1 (0.55) | IDO1 | |
| Hydrochloric Acid SCHEMBL21979356 | 0.88 | IDO1 (0.55) | IDO1 | |
| SCHEMBL22039274 | 0.87 | IDO1 (0.64) | IDO1 | |
| SCHEMBL20616586 | 0.87 | IDO1 (0.64) | IDO1 | |
| SCHEMBL31236009 | 0.83 | IDO1 (0.54) | IDO1GPR119HRH3 | |
| Hydrochloric Acid SCHEMBL21979441 | 0.83 | IDO1 (0.45) | IDO1 | |
| SCHEMBL17709203 | 0.82 | IDO1 (0.47) | IDO1GPR119HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10906924-B2 | Modulators of indoleamine 2,3-dioxygenase | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-02-02 | — | — | US | disclosed |
| US-20200165280-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165280-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, TPH1 | IDO1 1/4885GPR119 41/4885HRH3 1041/4885 |
| US-10906924-B2 | Modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, TPH1 | IDO1 1/4885GPR119 41/4885HRH3 1041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.