Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9653722 | 0.71 | TSHR (0.49) | RAB9AALDH1A1KMT2AMEN1POLB | |
| SCHEMBL30209768 | 0.64 | SMN1; SMN2 (0.59) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL12532565 | 0.64 | SMN1; SMN2 (0.59) | RAB9AALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8196836 | 0.64 | SMN1; SMN2 (0.59) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL13494354 | 0.63 | SMN1; SMN2 (0.57) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL3130853 | 0.63 | SMN1; SMN2 (0.57) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL10362600 | 0.62 | SMN1; SMN2 (0.52) | RAB9AALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9723100 | 0.62 | SMN1; SMN2 (0.52) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL28549090 | 0.62 | SMN1; SMN2 (0.61) | RAB9AALDH1A1TP53KMT2AMEN1 | |
| SCHEMBL5058907 | 0.62 | ALDH1A1 (0.42) | NPC1RAB9AALDH1A1TP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670772-B1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2011-08-17 | — | — | EP | disclosed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | DDT, CYP1B1, CYP51A1 | NPC1 4594/4885RAB9A 1773/4885ALDH1A1 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.