SCHEMBL220428

SCHEMBL220428

[CH2]c1ccc(N(CCCC)CCCC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.44
ERBB2 P04626 2/20 0.44
MAPT P10636 1/20 0.41
CNR2 P34972 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
NR1H2 P55055 6/20 0.39
NR1H3 Q13133 6/20 0.39
AR P10275 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
PSMD14 O00487 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2059149 0.96 EGFR (0.41) EGFRERBB2MAPTCNR2CHRM2
SCHEMBL2059148 0.94 EGFR (0.39) EGFRERBB2MAPTCNR2CHRM2
SCHEMBL28128909 0.92 CNR2 (0.41) EGFRERBB2CNR2INSR
SCHEMBL8019595 0.92 CNR2 (0.41) EGFRERBB2CNR2INSR
SCHEMBL7153351 0.89 EGFR (0.50) EGFRERBB2MAPTCNR2CHRM2
SCHEMBL220420 0.86 EGFR (0.41) EGFRERBB2MAPTCNR2AR
SCHEMBL768272 0.84 EGFR (0.47) EGFRERBB2MAPTCNR2CHRM2
SCHEMBL2014159 0.84 EGFR (0.47) EGFRERBB2MAPTCNR2CHRM2
SCHEMBL17663681 0.84 EGFR (0.47) EGFRERBB2MAPTCNR2CHRM2
SCHEMBL11803617 0.83 NR1H2 (0.42) EGFRERBB2MAPTCNR2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220404729-A1 TONER PARTICLES FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE AND TONER COMPOSITION FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE TOMOEGAWA CORPORATION (JP) 2022-12-22 US disclosed
EP-2690498-B1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC (JP) 2018-04-25 EP disclosed
US-8999620-B2 Toner for electrostatic latent image development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-04-07 US disclosed
US-8980515-B2 Magnetic toner for electrostatic latent image development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-03-17 US disclosed
US-20140045114-A1 MAGNETIC TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-02-13 US disclosed
US-20140038097-A1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-02-06 US disclosed
US-20140030647-A1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-01-30 US disclosed
EP-2690498-A1 Toner for electrostatic latent image development Kyocera Document Solutions Inc. (JP) 2014-01-29 EP disclosed
US-8163753-B2 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-04-24 US disclosed
EP-1501897-B1 METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES BASF SE (DE) 2012-03-14 EP disclosed
EP-0499266-B1 Endothelin antagonist TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-07-10 EP disclosed
EP-0626174-A2 Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-30 EP disclosed
US-5352659-A Polypeptide; hypotensive agents TAKEDA CHEMICAL INDUSTRIES (JP) 1994-10-04 US disclosed
US-5330960-A Benzindole dyes, colorfastness, photostability DAI NIPPON PRINTING CO., LTD. (JP) 1994-07-19 US disclosed
US-5306808-A Endothelin derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-26 US disclosed
EP-0547317-A1 Endothelin antagonists TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-23 EP disclosed
EP-0499266-A1 Endothelin antagonist TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-19 EP disclosed
EP-0470256-A1 PEPTIDE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1992-02-12 EP disclosed
WO-1991013089-A1 PEPTIDE DERIVATIVES AND PRODUCTION THEREOF TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-09-05 WO disclosed
US-4308164-A Novel yellow azo dyes and dichroic liquid crystal composition made therewith GENERAL ELECTRIC COMPANY (US) 1981-12-29 US disclosed