SCHEMBL220420

SCHEMBL220420

[CH2]c1ccc(N(CCC)CCC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.41
ERBB2 P04626 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 2/20 0.38
PSMD14 O00487 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
RECQL P46063 1/20 0.38
GFER P55789 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ESRRG P62508 2/20 0.37
CNR2 P34972 1/20 0.37
NPSR1 Q6W5P4 2/20 0.36
ALDH3A1 P30838 1/20 0.35
ALDH1A3 P47895 1/20 0.35
AR P10275 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150414 0.87 EGFR (0.47) EGFRERBB2L3MBTL1ALDH1A1MAPK1
SCHEMBL220428 0.86 EGFR (0.44) EGFRERBB2L3MBTL1ALDH1A1MAPK1
SCHEMBL2059148 0.85 EGFR (0.39) EGFRERBB2CNR2MAPT
SCHEMBL8019595 0.83 CNR2 (0.41) EGFRERBB2CNR2
SCHEMBL28128909 0.83 CNR2 (0.41) EGFRERBB2CNR2
SCHEMBL2059149 0.83 EGFR (0.41) EGFRERBB2ALDH1A1CNR2AR
SCHEMBL4224314 0.82 EGFR (0.44) EGFRERBB2L3MBTL1ALDH1A1MAPK1
SCHEMBL96331 0.80 ALDH1A1 (0.58) L3MBTL1ALDH1A1MAPK1PSMD14CYP3A4
SCHEMBL10300283 0.80 HRH3 (0.48) EGFRERBB2L3MBTL1ALDH1A1MAPK1
SCHEMBL7155728 0.80 HRH3 (0.48) EGFRERBB2L3MBTL1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220404729-A1 TONER PARTICLES FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE AND TONER COMPOSITION FOR DEVELOPING ELECTROSTATICALLY CHARGED IMAGE TOMOEGAWA CORPORATION (JP) 2022-12-22 US disclosed
EP-2690498-B1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC (JP) 2018-04-25 EP disclosed
US-8999620-B2 Toner for electrostatic latent image development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-04-07 US disclosed
US-8980515-B2 Magnetic toner for electrostatic latent image development KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2015-03-17 US disclosed
EP-2287218-B1 Pigment dispersant, pigment dispersion and method for producing the same, ink composition, ink set, and image-forming method FUJIFILM CORP (JP) 2014-12-03 EP disclosed
US-20140045114-A1 MAGNETIC TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-02-13 US disclosed
US-20140038097-A1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-02-06 US disclosed
US-20140030647-A1 TONER FOR ELECTROSTATIC LATENT IMAGE DEVELOPMENT KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2014-01-30 US disclosed
EP-2690498-A1 Toner for electrostatic latent image development Kyocera Document Solutions Inc. (JP) 2014-01-29 EP disclosed
US-8088876-B2 Copolymer, resin for electrophotographic functional component parts, developing roller, and electrophotographic apparatus CANON KASEI KABUSHIKI KAISHA (JP) 2012-01-03 US disclosed
EP-0499266-B1 Endothelin antagonist TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1996-07-10 EP disclosed
EP-0626174-A2 Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-11-30 EP disclosed
US-5352659-A Polypeptide; hypotensive agents TAKEDA CHEMICAL INDUSTRIES (JP) 1994-10-04 US disclosed
US-5306808-A Endothelin derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-26 US disclosed
EP-0547317-A1 Endothelin antagonists TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-06-23 EP disclosed
US-5149611-A Resin composing toner having nitrogen-containing polar group or fluorine functional group; stable, non-flying, clear images MINOLTA CAMERA KABUSHIKI KAISHA (JP) 1992-09-22 US disclosed
EP-0499266-A1 Endothelin antagonist TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-08-19 EP disclosed
EP-0470256-A1 PEPTIDE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1992-02-12 EP disclosed
WO-1991013089-A1 PEPTIDE DERIVATIVES AND PRODUCTION THEREOF TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-09-05 WO disclosed
EP-0435503-A1 Improvements in or relating to gylcopeptide derivatives ELI LILLY AND COMPANY (US) 1991-07-03 EP disclosed