Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042872 | 0.98 | KDM4E (0.53) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL10222750 | 0.84 | MAPT (0.56) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL6979523 | 0.81 | KDM4E (0.53) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL24095146 | 0.76 | KDM4E (0.51) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL9757149 | 0.76 | MAPT (0.47) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL25488091 | 0.76 | KDM4E (0.51) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL10902610 | 0.75 | MAPT (0.46) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL23342452 | 0.75 | MAPT (0.46) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL23374022 | 0.74 | AAK1 (0.47) | KDM4EMAPTHSD17B10NPC1RAB9A | |
| SCHEMBL2538594 | 0.73 | KDM4E (0.59) | KDM4EMAPTHSD17B10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020116971-A1 | COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF | 한국화학연구원 | 2020-06-11 | — | — | WO | disclosed |