Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043475 | 0.91 | IMPDH2 (0.75) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16939841 | 0.84 | IMPDH2 (0.81) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16939837 | 0.84 | IMPDH2 (0.81) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16939852 | 0.84 | IMPDH2 (0.81) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL22043480 | 0.84 | IMPDH2 (0.77) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL22043481 | 0.83 | IMPDH2 (1.00) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL22043469 | 0.83 | IMPDH2 (0.79) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL15597515 | 0.83 | IMPDH2 (0.78) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL15597702 | 0.83 | IMPDH2 (0.78) | IMPDH2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL15597524 | 0.83 | IMPDH2 (0.78) | IMPDH2KDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020112605-A1 | COMPOUNDS AND METHODS FOR TREATING CHRONIC MICROBIAL INFECTIONS | BRANDEIS UNIVERSITY (US) | 2020-06-04 | — | — | WO | disclosed |