Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 13/20 | 0.47 |
| ▸ | NPC1 | O15118 | 12/20 | 0.47 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044441 | 0.87 | PARP1 (0.55) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL22044396 | 0.81 | PARP1 (0.50) | PARP1LMNATDP1 | |
| SCHEMBL21589373 | 0.81 | PARP1 (0.53) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL24022744 | 0.80 | PARP1 (0.52) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL22043792 | 0.79 | PARP1 (0.50) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL103984 | 0.79 | PARP1 (0.59) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL29478724 | 0.79 | PARP1 (0.59) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL6841043 | 0.79 | PARP1 (0.59) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL26234540 | 0.79 | PARP1 (0.59) | PARP1RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL103985 | 0.79 | PARP1 (0.59) | PARP1RAB9ANPC1PKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020108720-A1 | NOVEL TETRAZINE COMPOUNDS FOR IN VIVO IMAGING | Københavns Universitet (DK) | 2020-06-04 | — | — | WO | disclosed |