Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22043777 | 0.87 | PARP1 (0.53) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| SCHEMBL21589373 | 0.83 | PARP1 (0.53) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| SCHEMBL22044257 | 0.82 | CYP2D6 (0.66) | L3MBTL1RAB9ATDP1NPC1SMN1; SMN2 | |
| SCHEMBL11774153 | 0.81 | CYP2D6 (0.66) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| SCHEMBL11774159 | 0.81 | CYP2D6 (0.66) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| SCHEMBL18938347 | 0.81 | KMT2A (0.61) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| Hydrochloric Acid SCHEMBL11769765 | 0.80 | CYP2D6 (0.64) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| Hydrochloric Acid SCHEMBL11769769 | 0.80 | CYP2D6 (0.64) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| SCHEMBL22043792 | 0.80 | PARP1 (0.50) | PARP1L3MBTL1RAB9ATDP1NPC1 | |
| SCHEMBL6841043 | 0.80 | PARP1 (0.59) | PARP1L3MBTL1RAB9ATDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228992-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | RIGSHOSPITALET (DK) | 2021-11-18 | — | — | WO | disclosed |
| EP-3909944-A1 | NUCLIDE LABELLED H-TETRAZINES AND USE THEREOF FOR PET AND SPECT PRETARGETED IMAGING AND RADIONUCLIDE THERAPY | Rigshospitalet (DK) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020108720-A1 | NOVEL TETRAZINE COMPOUNDS FOR IN VIVO IMAGING | Københavns Universitet (DK) | 2020-06-04 | — | — | WO | disclosed |