Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22044456 | 0.92 | MAPK1 (0.61) | RAB9ANPC1SMN1; SMN2MAPK1MAPK3 | |
| SCHEMBL22043984 | 0.91 | ITK (0.53) | RAB9ANPC1SMN1; SMN2MAPK1MAPK3 | |
| SCHEMBL22044120 | 0.83 | CHEK1 (0.46) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22044040 | 0.82 | ITK (0.62) | RAB9ANPC1SMN1; SMN2MAPK1MAPK3 | |
| SCHEMBL22044451 | 0.81 | ITK (0.53) | RAB9AMAPK1MAPK3GAAMEN1 | |
| SCHEMBL22044844 | 0.80 | ITK (0.48) | MAPK1MAPK3MAPK8ITK | |
| SCHEMBL22044104 | 0.79 | ITK (0.49) | MAPK1MAPK3ALDH1A1MEN1KMT2A | |
| SCHEMBL22044530 | 0.77 | MAPK1 (0.60) | MAPK1MAPK3MAPK8ITK | |
| SCHEMBL22043981 | 0.76 | FLT3 (0.55) | RAB9AMAPK1ITK | |
| SCHEMBL21802612 | 0.75 | MAP2K4 (0.61) | RAB9ANPC1MAPK1MAPK3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | Amcure Biosciences Pte. Ltd. (SG) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172521-A1 | Five-Membered-Fused-Six-Membered Aza-Aromatic Ring Compound, Preparation Method Thereof, Pharmaceutical Composition And Application Thereof | KRAS, NRAS, RASSF5 | RAB9A 51/4885NPC1 2933/4885SMN1; SMN2 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.