Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | RPA1 | P27694 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22045245 | 0.89 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL15180301 | 0.84 | RPA1 (0.57) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL30935867 | 0.84 | RPA1 (0.57) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL18934881 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL18425290 | 0.77 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL22045669 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL22045667 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL18463374 | 0.74 | AURKA (0.45) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL1687566 | 0.74 | KDM4E (0.48) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 | |
| SCHEMBL22045666 | 0.73 | TP53 (0.51) | KDM4EALDH1A1SMN1; SMN2HPGDRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020109524-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |