Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15180301 | 1.00 | RPA1 (0.57) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30166463 | 0.87 | KDM4E (0.49) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18053137 | 0.87 | KDM4E (0.49) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22045669 | 0.84 | KDM4E (0.45) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22045245 | 0.84 | KDM4E (0.50) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22045665 | 0.84 | KDM4E (0.50) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22045667 | 0.83 | KDM4E (0.56) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL20929343 | 0.80 | KDM4E (0.57) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13425234 | 0.78 | KDM4E (0.53) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13425232 | 0.78 | RPA1 (0.49) | RPA1KDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240147847-A1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240147847-A1 | ELECTRONIC DEVICES | NDUFS4, NDUFS3, NDUFS6 | RPA1 3413/4885KDM4E 842/4885ALDH1A1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.