Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22046593 | 0.81 | NPSR1 (0.40) | MAPTGFERNPSR1HTTALDH1A1 | |
| SCHEMBL19354162 | 0.76 | HTT (0.48) | MAPTGFERNPSR1HTTALDH1A1 | |
| SCHEMBL29552323 | 0.73 | HTT (0.48) | MAPTGFERNPSR1HTTALDH1A1 | |
| SCHEMBL2111661 | 0.73 | HTT (0.63) | MAPTGFERNPSR1HTTALDH1A1 | |
| SCHEMBL30476608 | 0.73 | HTT (0.63) | MAPTGFERNPSR1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL30055763 | 0.72 | HTT (0.61) | MAPTGFERNPSR1HTTALDH1A1 | |
| SCHEMBL3073777 | 0.72 | ALDH1A1 (0.51) | MAPTGFERNPSR1HTTALDH1A1 | |
| SCHEMBL3073776 | 0.70 | CYP2C19 (0.51) | MAPTGFERNPSR1HTTALDH1A1 | |
| SCHEMBL11621019 | 0.68 | ALDH1A1 (0.54) | MAPTGFERNPSR1HTTALDH1A1 | |
| Niacin SCHEMBL11124243 | 0.67 | ALDH1A1 (0.72) | MAPTGFERNPSR1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |