Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.61 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22047311 | 0.90 | AR (0.65) | ARPGR | |
| SCHEMBL20046577 | 0.90 | AR (0.64) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557879 | 0.89 | AR (0.66) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557880 | 0.89 | AR (0.66) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557805 | 0.88 | AR (0.64) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22557804 | 0.88 | AR (0.64) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL30349579 | 0.88 | AR (0.64) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL20046010 | 0.87 | AR (0.61) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22565038 | 0.86 | AR (0.72) | ARPGRTNKSPARP1PARP2 | |
| SCHEMBL22566109 | 0.86 | AR (0.72) | ARPGRTNKSPARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660004-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2020-06-03 | — | — | EP | disclosed |