Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 17/20 | 1.00 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246840 | 0.94 | HCAR3 (0.97) | HCAR3HCAR2EPHX2 | |
| Hydrochloric Acid SCHEMBL11180843 | 0.93 | HCAR3 (0.94) | HCAR3HCAR2EPHX2 | |
| SCHEMBL186474 | 0.90 | HCAR3 (1.00) | HCAR3HCAR2FYN | |
| SCHEMBL31292064 | 0.84 | HCAR3 (0.73) | HCAR3HCAR2 | |
| SCHEMBL186420 | 0.83 | HCAR3 (1.00) | HCAR3HCAR2 | |
| SCHEMBL18193683 | 0.83 | HCAR3 (0.74) | HCAR3HCAR2 | |
| SCHEMBL9592348 | 0.82 | HCAR3 (0.70) | HCAR3EPHX2CNR2 | |
| SCHEMBL7230169 | 0.82 | HCAR3 (0.73) | HCAR3HCAR2 | |
| SCHEMBL1680894 | 0.82 | HCAR3 (0.76) | HCAR3HCAR2EPHX2CNR2 | |
| SCHEMBL3562313 | 0.81 | HCAR3 (0.71) | HCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3660004-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | Arvinas Operations, Inc. (US) | 2020-06-03 | — | — | EP | disclosed |