Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22048043 | 0.84 | KDM4E (0.53) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL22048061 | 0.82 | ESR2 (0.42) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL22048083 | 0.81 | KMT2A (0.53) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL22048237 | 0.80 | KDM4E (0.49) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL27994759 | 0.80 | MAPK1 (0.50) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL22048066 | 0.79 | ESR2 (0.41) | KDM4EL3MBTL1ESR2DDB1CRBN | |
| SCHEMBL22048052 | 0.78 | HSD11B1 (0.33) | ESR2HSD11B1DDB1CRBNCNR2 | |
| SCHEMBL22048063 | 0.78 | PSMB8 (0.37) | ESR2HSD11B1DDB1CRBNCNR2 | |
| SCHEMBL744509 | 0.77 | ESR2 (0.56) | SMN1; SMN2ESR2HSD11B1PDE4APDE4B | |
| SCHEMBL22048034 | 0.76 | ESR2 (0.44) | KDM4EGLAHTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108579-A1 | AMINO-SUBSTITUTED PYRIDONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 上海海雁医药科技有限公司 | 2020-06-04 | — | — | WO | disclosed |