⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29564726 | 1.00 | — | — | |
| SCHEMBL27599895 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL30986896 | 0.98 | P2RX7 (0.60) | — | |
| Hydrochloric Acid SCHEMBL27472830 | 0.98 | P2RX7 (0.60) | — | |
| SCHEMBL29495233 | 0.98 | P2RX7 (0.60) | — | |
| Hydrochloric Acid SCHEMBL25429260 | 0.98 | P2RX7 (0.60) | — | |
| Benzene SCHEMBL14741825 | 0.96 | P2RX7 (0.58) | — | |
| Trimethylammonium SCHEMBL27900614 | 0.92 | P2RX7 (0.55) | — | |
| Succinic Acid SCHEMBL4542376 | 0.89 | P2RX7 (0.56) | — | |
| Trifluoroacetic Acid SCHEMBL30547497 | 0.87 | P2RX7 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250230154-A1 | COMPOUND HAVING SHP2 PROTEIN DEGRADING ACTIVITY, AND MEDICAL USES THEREOF | UBIX THERAPEUTICS, INC. (KR) | 2025-07-17 | — | — | US | claimed |
| CN-120092003-A | CDK protein degrading agents, pharmaceutical compositions and therapeutic uses | 拜欧斯瑞克斯公司 | 2025-06-03 | — | — | CN | claimed |
| EP-3728234-B1 | RADIOLABELED COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2025-05-14 | — | — | EP | claimed |
| CN-119907790-A | Pyrazole amide insecticidal agents | FMC公司 | 2025-04-29 | — | — | CN | claimed |
| EP-3827831-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NONALCOHOLIC STEATOHEPATITIS | J2H BIOTECH INC (KR) | 2025-03-26 | — | — | EP | claimed |
| EP-4522613-A1 | CDK PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | Biotheryx, Inc. (US) | 2025-03-19 | — | — | EP | claimed |
| CN-119504710-A | PROTACs compound for targeted degradation of PRMT5 and application thereof | 昆明医科大学 | 2025-02-25 | — | — | CN | claimed |
| EP-4069691-B1 | SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2024-09-18 | — | — | EP | claimed |
| CN-118530286-A | Double-function pyrimidine monoamide ligand-based complex with efficient heterogeneous organic catalysis and electrocatalytic function and application thereof | 渤海大学 | 2024-08-23 | — | — | CN | claimed |
| US-12011443-B2 | Pharmaceutical composition for preventing or treating nonalcoholic steatohepatitis | J2H BIOTECH INC. (KR) | 2024-06-18 | — | — | US | claimed |
| WO-2004019933-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| CN-1407985-A | Heterocyclic dihydropyrimidines as potassium channel inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2003-04-02 | — | — | CN | claimed |
| WO-2002048116-A2 | INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-06-20 | — | — | WO | claimed |
| CN-1332743-A | Cell adhesion-inhibiting antinflammatory compounds | ABBOTT CO (US) | 2002-01-23 | — | — | CN | claimed |
| EP-0522915-B1 | Pyrimidine-4-carboxamide derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1996-03-13 | — | — | EP | claimed |
| US-5330985-A | Adrenergic blocking agents; urogenital disorders | SYNTHELABO (FR) | 1994-07-19 | — | — | US | claimed |
| US-5244901-A | Multistage preparation by starting with a phenylpiperazine and an epoxide or chloro alcohol containing a phthalimido group; use to treat disorders involving hyperactivity of the alpha 1-adrenergic system | SYNTHELABO (FR) | 1993-09-14 | — | — | US | claimed |
| EP-0522915-A1 | Pyrimidine-4-carboxamide derivatives, their preparation and their use in therapeutics | SYNTHELABO (FR) | 1993-01-13 | — | — | EP | claimed |
| CN-1067884-A | Pyrimidine-4-carboxamides derivatives and method for making and medical applications | SYNTHELABO (FR) | 1993-01-13 | — | — | CN | claimed |
| EP-0022494-B1 | BETA-LACTAM-COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-02-23 | — | — | EP | claimed |