⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225564 | 0.81 | — | — | |
| SCHEMBL3769635 | 0.78 | — | — | |
| SCHEMBL19773526 | 0.78 | — | — | |
| SCHEMBL841142 | 0.75 | CA12 (0.47) | — | |
| SCHEMBL9302179 | 0.75 | CA12 (0.47) | — | |
| SCHEMBL134391 | 0.73 | — | — | |
| SCHEMBL5614099 | 0.72 | — | — | |
| SCHEMBL24680969 | 0.71 | — | — | |
| SCHEMBL3024582 | 0.71 | — | — | |
| SCHEMBL16864481 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597699-B2 | MEK inhibitors and methods of their use | EXELIXIS, INC. (US) | 2023-03-07 | — | — | US | disclosed |
| US-20200283383-A1 | MEK Inhibitors and Methods of Their Use | EXELIXIS, INC. | 2020-09-10 | — | — | US | disclosed |
| US-7981322-B2 | Use of a metal organosilicate polymer for the protection of compounds sensitive to oxidation and/or to electromagnetic radiation | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2011-07-19 | — | — | US | disclosed |
| US-20090159859-A1 | USE OF A METAL ORGANOSILICATE POLYMER FOR THE PROTECTION OF COMPOUNDS SENSITIVE TO OXIDATION AND/OR TO ELECTROMAGNETIC RADIATION | COMMISSARIAT A L'ENERGIE ATOMIQUE | 2009-06-25 | — | — | US | disclosed |