Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM2 | P31350 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.36 |
| ▸ | MERTK | Q12866 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050225 | 0.79 | P4HTM (0.58) | RRM2HCAR3P4HTMLMNAKDM4E | |
| SCHEMBL21988097 | 0.77 | NFKB1 (0.62) | P4HTMSMN1; SMN2LMNAKDM4ECYP1A2 | |
| SCHEMBL13954312 | 0.70 | P4HTM (0.61) | RRM2HCAR3P4HTMLMNAKDM4E | |
| SCHEMBL14197601 | 0.68 | RRM2 (0.48) | RRM2HCAR3KDM4EMAPTMEN1 | |
| SCHEMBL7664958 | 0.67 | RRM2 (0.47) | RRM2HCAR3SMN1; SMN2LMNAKDM4E | |
| SCHEMBL2171131 | 0.67 | RRM2 (0.47) | RRM2HCAR3SMN1; SMN2TYRO3MERTK | |
| SCHEMBL26559603 | 0.64 | RRM2 (0.48) | RRM2HCAR3SMN1; SMN2LMNAKDM4E | |
| SCHEMBL181559 | 0.64 | MAPT (0.52) | LMNAKDM4ECYP1A2CYP3A4MAPT | |
| SCHEMBL22854537 | 0.64 | HTT (0.56) | SMN1; SMN2LMNAKDM4EMEN1TSHR | |
| SCHEMBL18405340 | 0.64 | P4HTM (0.60) | HCAR3P4HTMLMNAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172534-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172534-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | RRM2 2459/4885HCAR3 2347/4885P4HTM 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.