Trolamine

Trolamine

SCHEMBL220505

CCN(CC)CC.OCCN(CCO)CCO

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.52
HPGD P15428 2/20 0.52
MAPK1 P28482 2/20 0.52
CYP2C9 P11712 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 1/20 0.52
MAPT P10636 4/20 0.42
ALDH1A1 P00352 6/20 0.39
ALDH2 P05091 1/20 0.39
CYP2D6 P10635 2/20 0.38
KDM4E B2RXH2 3/20 0.33
ALOX15 P16050 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ARG1 P05089 1/20 0.33
ARG2 P78540 1/20 0.33
LMNA P02545 1/20 0.33
SLC29A1 Q99808 1/20 0.32
CYP2C19 P33261 1/20 0.32
TSHR P16473 1/20 0.31
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL2160601 0.94 CYP1A2 (0.48) CYP1A2HPGDMAPK1CYP2C9HIF1A
Trolamine SCHEMBL5034081 0.94 CYP1A2 (0.48) CYP1A2HPGDMAPK1CYP2C9HIF1A
Trolamine SCHEMBL5032871 0.94 CYP1A2 (0.48) CYP1A2HPGDMAPK1CYP2C9HIF1A
Trolamine SCHEMBL11520004 0.93 CYP1A2 (0.58) CYP1A2HPGDMAPK1CYP2C9HIF1A
Trolamine SCHEMBL22749413 0.93 CYP1A2 (0.52) CYP1A2HPGDMAPK1CYP2C9HIF1A
SCHEMBL2845423 0.90 CYP1A2 (0.50) CYP1A2HPGDMAPK1CYP2C9HIF1A
SCHEMBL21531945 0.90 CYP1A2 (0.56) CYP1A2HPGDMAPK1CYP2C9HIF1A
Diethylaminoethanol SCHEMBL3114 0.90
Diethylaminoethanol SCHEMBL10699915 0.90
SCHEMBL35602 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4200370-B1 HEAT STABLE INKJET INKS SUN CHEMICAL BV (NL) 2024-05-29 EP disclosed
US-20240034893-A1 HEAT STABLE INKJET INKS SUN CHEMICAL CORPORATION (US) 2024-02-01 US disclosed
WO-2023220577-A1 6,6A,7,8,9,10-HEXAHYDRO-5H-PYRAZINO[1',2':4,5]PYRAZINO[2,3-C]PYRIDAZINE DERIVATIVES AS SMARCA4 PROTEIN DEGRADERS FOR THE TREATMENT OF CANCER PRELUDE THERAPEUTICS, INCORPORATED (US) 2023-11-16 WO disclosed
US-20230348746-A1 LAMINATION PRIMERS AND INKS FOR AQUEOUS INKJET PRINTING SUN CHEMICAL CORPORATION (US) 2023-11-02 US disclosed
EP-4240743-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE Prelude Therapeutics, Incorporated (US) 2023-09-13 EP disclosed
EP-3647382-B1 INKJET INK FOR TEXTILE PRINTING, INK CARTRIDGE, INK SET, AND INKJET TEXTILE PRINTING METHOD FUJIFILM CORP (JP) 2023-09-06 EP disclosed
EP-4200370-A1 HEAT STABLE INKJET INKS Sun Chemical Corporation (US) 2023-06-28 EP disclosed
CN-113544189-B Polycarbonate diol and use thereof 旭化成株式会社 2023-02-24 CN disclosed
EP-4127081-A1 LAMINATION PRIMERS AND INKS FOR AQUEOUS INKJET PRINTING Sun Chemical Corporation (US) 2023-02-08 EP disclosed
CN-112940213-B Polyurea resin 旭化成株式会社 2022-11-04 CN disclosed
CN-100515500-C Deodorant and deodorizing article IDEMITSU TECHNOFINE CO LTD (JP) 2009-07-22 CN disclosed
US-20080003529-A1 (Meth)Acrylate, Polymer and Resist Composition MITSUBISHI RAYON CO., LTD. (JP) 2008-01-03 US disclosed
CN-1878573-A Deodorant and deodorizing article IDEMITSU TECHNOFINE CO LTD (JP) 2006-12-13 CN disclosed
EP-0872491-B1 Pressure-resistant absorbent resin, disposable diaper using the resin and absorbent resin, and method for production thereof NIPPON CATALYTIC CHEM IND (JP) 2006-05-17 EP disclosed
US-6184433-B1 RESIN WHICH MANIFESTS A HIGH RATIO OF WATER ABSORPTION CAPACITY UNDER NO PRESSURE AND UNDER PRESSURE AND A HIGH SPEED OF ABSORPTION UNDER NO PRESSURE AND UNDER PRESSURE; NO LEAKAGE WHEN BABY MOVES AND EXERTS INCESSANTLY VARYING LOAD NIPPON SHOKUBAI CO., LTD. (JP) 2001-02-06 US disclosed
EP-0872491-A1 Pressure-resistant absorbent resin, disposable diaper using the resin and absorbent resin, and method for production thereof NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-21 EP disclosed
US-5081245-A Selective antitumor agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-01-14 US disclosed
EP-0356765-A2 Carboxylic acid derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-03-07 EP disclosed
US-4522693-A Photopolymerizable composition with acylphosphine sulfide photoinitiator and method BASF AKTIENGESELLSCHAFT (DE) 1985-06-11 US disclosed
US-4139672-A UNDERVOATING, ELECTROCOATING, INTERMEDIATE COAT CONTAINING METAL FARBOXYLIC ACID MITSUI TOATSU CHEMICALS, INC. (JP) 1979-02-13 US disclosed